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N-Methylcyclohexanamine

CAS No.: 100-60-7

Category

Cat.NO.:A678231  Purity:98%

Product Details of [ 100-60-7 ]

CAS No. : 100-60-7
Formula :

C7H15N

M.W :

113.20

SMILES Code :
CNC1CCCCC1
MDL No. : MFCD00003832
InChI Key : XTUVJUMINZSXGF-UHFFFAOYSA-N
Pubchem ID : 7514

Safety of [ 100-60-7 ]

GHS Pictogram:
Signal Word: Danger
Hazard Statements: H226-H302+H332-H314
Precautionary Statements: P261-P270-P240-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405-P501
Class: 8(3)
UN#: 2734
Packing Group:

Application In Synthesis of [ 100-60-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 100-60-7 ]

[ 100-60-7 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 100-60-7 ]
  • [ 3034-48-8 ]
  • [ 21166-13-2 ]
  • 2
  • [ 100-60-7 ]
  • [ 3034-48-8 ]
  • [ 21166-12-1 ]
  • 3
  • [ 100-60-7 ]
  • [ 1227934-69-1 ]
  • [ 1227934-71-5 ]
  • [ 1227934-99-7 ]
Yield Reaction Conditions Operation in experiment
2-(cyclohexyl(methyl)amino)-4-trifluoromethyloxazole-5-carboxylic Acid (A-34) Intermediate A-34 was prepared by the general procedure for intermediate A-4, by using A-2 and N-methylcyclohexylamine as starting materials. MS (M+1): 293.
  • 4
  • [ 100-60-7 ]
  • [ 161957-56-8 ]
  • 3-bromo-N-cyclohexyl-2-fluoro-N-methyl-benzamide [ No CAS ]
Yield Reaction Conditions Operation in experiment
With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; for 3h; 5a) 3-Bromo-N-cyclohexyl-2-fluoro-N-methyl-benzamide A solution of 3-bromo-2-fluoro-benzoic acid (0.50 g, 2.28 mmol), HATU (0.868 g, 2.28 mmol), N-cyclohexyl-N-methylamine (0.297 g, 2.63 mmol) and DIPEA (0.590 g, 4.57 mmol) in DCM (15 mL) was stirred for 3 h. The mixture was washed with aqueous NaHC03 and dried by passage through a phase separation cartridge. Concentration to dryness gave the crude product (0.905 g, quantative), used without further purification. LC-MS m/z 314 (M + H) +, 1 .50 (ret. time).
 

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