Cat.NO.:A103389 Purity:97%
Product Details of [ 1011487-94-7 ]
| CAS No. : | 1011487-94-7 |
| Formula : |
C5H5ClN2O |
| M.W : |
144.56
|
| SMILES Code : | OCC1=CC=C(Cl)N=N1 |
| MDL No. : | MFCD11977451 |
| InChI Key : | NEWRIXKPAGUARA-UHFFFAOYSA-N |
| Pubchem ID : | 20557609 |
Safety of [ 1011487-94-7 ]
| GHS Pictogram: |  |
| Signal Word: | Warning |
| Hazard Statements: | H302-H315-H319-H332-H335 |
| Precautionary Statements: | P280-P305+P351+P338-P310 |
Application In Synthesis of [ 1011487-94-7 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1011487-94-7 ]
[ 1011487-94-7 ] Synthesis Path-Downstream 1~1
- 1
[ 65202-50-8 ]
[ 1011487-94-7 ]
| Yield | Reaction Conditions | Operation in experiment |
|---|---|---|
| Example 87 [0264] Formula 88] [0265] 1) In tetrahydrofuran (100 mL) was dissolved methyl 6-chloropyridazin-3-carboxylate (1.726 g), the solution was cooled to 0°C, 1M diisobutyaluminum hydride-tetrahydro- furan solution (20 mL) was added dropwise to the solution, and the mixture was stirred at the same temperature for 20 minutes. To the reaction mixture were successively added water (10 mL) and IN hydrochloric acid (20 mL) at 0°C. After adding a saturated aqueous sodium bicarbonate solution to the mixture at room temperature, the mixture was extracted with chloroform. The extract was dried over anhydrous sodium sulfate, and the residue obtained by concentrating the extract under reduced pressure was purified by silica gel column chromatography (n-hexane: ethyl acetate=90: 10 to 25:75) to obtain (6-chloropyridazin-3-yl)methanol (177 mg).MS (m/z): 147/145 [M+H]+ |
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