Cat.NO.:A1522806 Purity:95%
Product Details of [ 1006619-83-5 ]
| CAS No. : | 1006619-83-5 |
| Formula : |
C8H9ClN2O |
| M.W : |
184.62
|
| SMILES Code : | O=C(N)C1=CC(Cl)=CC(C)=C1N |
| MDL No. : | MFCD11044518 |
| InChI Key : | GJPVEWHLNAWLNW-UHFFFAOYSA-N |
| Pubchem ID : | 44887012 |
Safety of [ 1006619-83-5 ]
| GHS Pictogram: |  |
| Signal Word: | Warning |
| Hazard Statements: | H302-H317-H319 |
| Precautionary Statements: | P261-P264-P270-P272-P280-P301+P312+P330-P302+P352-P305+P351+P338-P333+P313-P337+P313-P363-P501 |
Application In Synthesis of [ 1006619-83-5 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1006619-83-5 ]
[ 1006619-83-5 ] Synthesis Path-Downstream 1~1
- 1
[ 1006619-83-5 ]
[ 35344-95-7 ]
- 6-chloro-8-methyl-2-(1H-pyrazol-4-yl)-2,3-dihydroquinazolin-4(1H)-one [ No CAS ]
| Yield | Reaction Conditions | Operation in experiment |
|---|---|---|
| 50% | In methanol; at 20℃; | General procedure: Cyanuric chloride (28mg, 0.15mmol) was added to a mixture of 3a, 3b, 3k or 3s (1mmol) and 4b-4h (1.2mmol) in MeOH or DMSO (3mL). The mixture was stirred at room temperature for 0.5?2h. After completion, the mixture was extracted with EtOAc three times. The combined organic layers were washed with brine, dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography eluting with CH2Cl2/MeOH (30/1) to afford D1-D12. |
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