Electrochemistry

Easy CDMO has developed a series of electrochemical oxidation-promoted transition metal-catalyzed selective functionalization of carbon-hydrogen bonds to achieve the selective oxidation of alkanes C(sp3)–H bonds (J. Am. Chem. Soc. 2017, 139, 3293), the selective amination of aromatic C(sp2)–H bonds (J. Am. Chem. Soc. 2018, 140, 11487) and the choice of olefin C(sp2)–H bonds Cyclization and other reactions (J. Am. Chem. Soc. 2019, 141, 18970; Acc. Chem. Res. 2020, 53, 300). At the same time, in the coupling reaction promoted by electrochemical reduction, nickel-catalyzed (hetero)aryl bromide or chlorinated thioetherification reaction (Angew. Chem. Int. Ed. 2019, 58, 5033) and nickel-catalyzed Migration coupling reaction between aryl halides and alkyl halides (Angew. Chem. Int. Ed. 2020, 59, 6520)