Products

Tenovin-3

Tenovin-3

Tenovin-3

CAS No.: 1011301-27-1

Category Products

Cat.NO.:A501104 Purity:98%

Product Details of Tenovin-3

CAS No. :	1011301-27-1
Formula :	C₁₈H₂₁N₃OS
M.W :	327.44
SMILES Code :	S=C(NC1=CC=C(C=C1)N)NC(C2=CC=C(C=C2)C(C)(C)C)=O
MDL No. :	MFCD25976437
InChI Key :	NLAXTZPUTNGRDU-UHFFFAOYSA-N
Pubchem ID :	24772097

Safety of Tenovin-3

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H302
Precautionary Statements:	P280-P305+P351+P338

Isoform Comparison

Biological Activity

Target

SIRT2

Protocol

Bio Calculators

Preparing Stock Solutions

1mg

5mg

10mg

1 mM

5 mM

10 mM

3.05mL

0.61mL

0.31mL

15.27mL

3.05mL

1.53mL

30.54mL

6.11mL

3.05mL

References

[1]Lain S, Hollick JJ, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63.

[2]McCarthy AR, Pirrie L, et al. Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins. Bioorg Med Chem. 2012 Mar 1;20(5):1779-93.

[3]Burgeson JR, Moore AL, et al. SAR analysis of a series of acylthiourea derivatives possessing broad-spectrum antiviral activity. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4263-72.

[4]Lain S, Hollick JJ, Campbell J, Staples OD, Higgins M, Aoubala M, McCarthy A, Appleyard V, Murray KE, Baker L, Thompson A, Mathers J, Holland SJ, Stark MJ, Pass G, Woods J, Lane DP, Westwood NJ. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63. doi: 10.1016/j.ccr.2008.03.004. PMID: 18455128; PMCID: PMC2742717.

[5]McCarthy AR, Pirrie L, Hollick JJ, Ronseaux S, Campbell J, Higgins M, Staples OD, Tran F, Slawin AM, Lain S, Westwood NJ. Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins. Bioorg Med Chem. 2012 Mar 1;20(5):1779-93. doi: 10.1016/j.bmc.2012.01.001. Epub 2012 Jan 12. PMID: 22304848.

[6]Burgeson JR, Moore AL, Boutilier JK, Cerruti NR, Gharaibeh DN, Lovejoy CE, Amberg SM, Hruby DE, Tyavanagimatt SR, Allen RD 3rd, Dai D. SAR analysis of a series of acylthiourea derivatives possessing broad-spectrum antiviral activity. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4263-72. doi: 10.1016/j.bmcl.2012.05.035. Epub 2012 May 17. PMID: 22664128.

Details

Reviews

There are no reviews yet.

Be the first to review “Tenovin-3”

Previous

Methyl 2-bromo-4-hydroxybenzoate

Next

7-Bromo-1-chlorophthalazine