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GSK369796 2HCl

CAS No.: 1010411-21-8

Category

Cat.NO.:A984981  Purity:99%

Product Details of GSK369796 2HCl

CAS No. : 1010411-21-8
Formula :

C20H24Cl3N3O

M.W :

428.78

SMILES Code :
OC1=CC(NC2=CC=NC3=CC(Cl)=CC=C23)=CC=C1CNC(C)(C)C.[H]Cl.[H]Cl
Synonyms :
GSK369796 (hydrochloride); GSK369796 Dihydrochloride; N-tert-butylisoquine
MDL No. : MFCD16627991
InChI Key : UDVALKJFXQVZSI-UHFFFAOYSA-N
Pubchem ID : 51071988

Safety of GSK369796 2HCl

GHS Pictogram:
Signal Word: Warning
Hazard Statements: H315-H319-H335
Precautionary Statements: P261-P305+P351+P338

Isoform Comparison

Name Potassium Channel Purity
Tolbutamide 98%
Glimepiride ++++ 97%
Dronedarone HCl 95%
Gliquidone ++ 99%
TRAM-34 +++ 98%
Glibenclamide 98%
Amiodarone HCl 97%
Gliclazide ++ 98%
Repaglinide 98%
Dofetilide 98%
Nateglinide 99%
Quinine HCl dihydrate 98%
ML133 HCl + 99%

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.33mL

0.47mL

0.23mL

11.66mL

2.33mL

1.17mL

23.32mL

4.66mL

2.33mL

Dissolving Methods

Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.

Protocol 1
Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline
Solubility: ≥ 2.5 mg/mL (5.83 mM); Clear solution
Protocol 2
Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (5.83 mM); Clear solution

References

 

Details

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