Products

RG3039

RG3039

RG3039

CAS No.: 1005504-62-0

Category Products

Cat.NO.:A129874 Purity:98%

Product Details of RG3039

CAS No. :	1005504-62-0
Formula :	C₂₁H₂₃Cl₂N₅O
M.W :	432.35
SMILES Code :	NC1=NC(N)=C2C(OCC3CCN(CC4=C(Cl)C=CC=C4Cl)CC3)=CC=CC2=N1
Synonyms :	PF-06687859; Quinazoline 495; PF 6687859
MDL No. :	MFCD28716151
InChI Key :	MNLHFGXIUJNDAF-UHFFFAOYSA-N
Pubchem ID :	53258905

Safety of RG3039

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H302-H315-H319-H335
Precautionary Statements:	P261-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators

Preparing Stock Solutions

1mg

5mg

10mg

1 mM

5 mM

10 mM

2.31mL

0.46mL

0.23mL

11.56mL

2.31mL

1.16mL

23.13mL

4.63mL

2.31mL

References

[1]Gopalsamy A, Narayanan A, Liu S, et al. Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA). J Med Chem. 2017;60(7):3094-3108

[2]Gogliotti RG, Cardona H, Singh J, et al. The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models. Hum Mol Genet. 2013;22(20):4084-4101

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