Cat.NO.:A482974 Purity:95%
Product Details of 2,4,5,6-Tetraaminopyrimidine
| CAS No. : | 1004-74-6 |
| Formula : |
C4H8N6 |
| M.W : |
140.15
|
| SMILES Code : | NC1=NC(N)=C(N)C(N)=N1 |
| Synonyms : |
2,4,5,6-Tetraaminopyrimidine
|
| MDL No. : | MFCD00152825 |
| InChI Key : | PZRKPUQWIFJRKZ-UHFFFAOYSA-N |
| Pubchem ID : | 70487 |
Safety of 2,4,5,6-Tetraaminopyrimidine
| GHS Pictogram: |  |
| Signal Word: | Warning |
| Hazard Statements: | H315-H319 |
| Precautionary Statements: | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362 |
Application In Synthesis of 2,4,5,6-Tetraaminopyrimidine
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1004-74-6 ]
[ 1004-74-6 ] Synthesis Path-Downstream 1~2
- 1
[ 1004-74-6 ]
[ 96-26-4 ]
[ 945-24-4 ]
| Yield | Reaction Conditions | Operation in experiment |
|---|---|---|
| 790mg (3.3mmol) of 2,4,5,6 four amino pyrimidine sulfate (Compound 10) was dissolved in 15ml of water, to which was dissolved in 4ml of water was added 690mg (3.3mmol) of barium chloride, the reaction solution was set to open bath for 10 minutes. After spontaneous cooling to room temperature, filtered and precipitated barium sulfate precipitate was washed with water to about 4ml. The combined filtrate and washings were diluted with water to about 50ml, and then added to a previously added 900mg (10mmol) 50ml4M sodium acetate solution of 1,3-dihydroxyacetone, the reaction mixture was stirred at room temperature 24h. After which the reaction flask was transferred to a 4 C refrigerator stored 12 h, then the precipitate was filtered off and washed with ice-water. The precipitate was suspended in 40ml of water, heated to boiling, a small amount of added dropwise 1N aqueous sodium hydroxide solution was suspendedIt was completely clarified. Slowly add 0.2g of activated carbon, stir hot filtration (also preheated funnel). After cooling to room temperature with 1N aqueous hydrochloric acid solution adjusting pH to about 6.0, and the reaction solution was cooled at 4 degree refrigerator 12h. The precipitate was filtered off, washed with ice water, ethanol, ethanol – ether (50:50), washed with ether, and dried in vacuo to give 350mg after compound (11), white solid, a yield of 55.2% |
- 2
- [ 1004-74-6 ]
[ 1798-83-0 ]- 6,8-diamino-4-(4-chlorophenyl)-2,3-dihydropyrimido[4,5-b][1,4]diazepine [ No CAS ]
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